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ItemThe staphylococcal accessory regulator, SarA, is an RNA-binding protein that modulates the mRNA turnover properties of late-exponential and stationary phase Staphylococcus aureus cells(Frontiers in Cellular and Infection Microbiology, 2012-03) Anderson, Kelsi L., PhD Morrison, John M. Beenken, Karen E. Smeltzer, Mark S. Dunman, Paul M.The modulation of mRNA turnover is gaining recognition as a mechanism by which Staphylococcus aureus regulates gene expression, but the factors that orchestrate alterations in transcript degradation are poorly understood. In that regard, we previously found that 138 mRNA species, including transcripts coding for the virulence factors protein A (spa) and collagen-binding protein (cna), are stabilized in a sarA-dependent manner during exponential phase growth, suggesting that SarA directly or indirectly affects the RNA turnover properties of these transcripts. Herein, we expanded our characterization of the effects of sarA on mRNA turnover during late-exponential and stationary phases of growth. Results revealed that the locus affects the RNA degradation properties of cells during both growth phases. Further, using gel mobility shift assays and RIP-Chip, it was found that SarA protein is capable of binding mRNA species that it stabilizes both in vitro and within bacterial cells. Taken together, these results suggest that SarA post-transcriptionally regulates S. aureus gene expression in a manner that involves binding to and consequently altering the mRNA turnover properties of target transcripts. ItemRisk factors for early childhood infection of human herpesvirus-8 in Zambian children: The role of early childhood feeding practices(American Association for Cancer Research, 2014-02) Crabtree, Kay L.; Wojcicki, Janet M.; Minhas, Veenu; Smith, David R.; Kankasa, Chipepo; Mitchell, Charles D.; Wood, CharlesBACKGROUND: Human herpesvirus-8 (HHV-8) infection in early childhood is common throughout sub-Saharan Africa with prevalence increasing throughout childhood. Specific routes of transmission have not been clearly delineated, though HHV-8 is present in high concentrations in saliva. METHODS: To understand the horizontal transmission of HHV-8 within households to children, we enrolled for cross-sectional analysis, 251 households including 254 children, age two and under, in Lusaka, Zambia. For all children, plasma was screened for HHV-8 and HIV type I (HIV-1) and health and behavioral questionnaires were completed. Multilevel logistic regression analysis was conducted to assess independent factors for HHV-8 infection in children. RESULTS: Risk factors for HHV-8 infection included increasing number of HHV-8-positive household members [OR = 2.5; 95% confidence interval (CI), 1.9-3.3; P < 0.01] and having a primary caregiver who tested the temperature of food with their tongue before feeding the child (OR = 2.4; 95% CI, 1.93-3.30; P =0.01). Breastfeeding was protective against infection with HHV-8 for children (OR= 0.3; 95% CI, 0.16-0.72; P < 0.01). CONCLUSIONS: These results indicate that exposure to HHV-8 in the household increases risk for early childhood infection, with specific feeding behaviors likely playing a role in transmission. IMPACT: Interventions to protect children from infection should emphasize the possibility of infection through sharing of foods. ItemActive learning in the undergraduate classroom: A journal-club experience designed to accentuate course content(National Association of Biology Teachers, 2016) Anderson, Kelsi L.Students in the natural sciences should be prepared as undergraduates to read and apply concepts from the scientific literature. I describe a strategy that enforced the necessity to deliver high volumes of content while incorporating an active-learning technique. Students were assigned to read and discuss articles from the scientific literature that complemented content being delivered via traditional lecture. Students were encouraged to participate by coming to class prepared with written questions, and discussion was directed by instructor-prepared prompts. Students were assessed via low-stakes assignments based primarily on participation. This teaching method has proved effective, as verbally reported by past students who are currently enrolled in graduate programs. These students report feeling more prepared than their peers to discuss and learn from the scientific literature. ItemCharacterizing the Antibacterial Properties and Transcriptional Alternations Induced by Lemongrass Oil in Staphylococcus aureus(The Journal of Experimental Microbiology & Immunology+, 2017) Christensen, Collin J.; Anderson, Kelsi LEssential oils have risen in popularity as “all natural” alternatives used to treat a myriad of conditions. To begin to elucidate the antibacterial properties of essential oils, we tested the effectiveness of lemongrass oil (LGO), tea tree oil (TTO), and willow bark extract (WBE) against Staphylococcus aureus growth. To do so, a Methicillin-Resistant strain of Staphylococcus aureus (USA300) was exposed to each oil using disk diffusion assays. Of the oils, LGO had the greatest zone of inhibition. The Minimum Inhibitory Concentration (MIC) of both LGO and citral (the primary chemical component of LGO) was determined in macro-broth cultures; exposure to increased concentrations of each resulted in dramatic cell death as determined by cell growth assays. To begin to determine the molecular mechanisms underlying the observed antibacterial effects, we exposed cells to a sub-inhibitory concentration of citral and hybridized the RNA to Affymetrix GeneChips®. Transcripts differentially affected in citral- versus mocktreated cells represent virulence factors, hypothetical proteins, and intergenic regions. Taken together, these results demonstrate that LGO exhibits antibacterial properties against a highly pathogenic bacterial species that is exceedingly resistant to the currently available antibiotics. ItemAssociation of household food- and drink-sharing practices with human herpesvirus 8 seroconversion in a cohort of Zambian children(Oxford University Press for the Infectious Diseases Society of America, 2017-10-17) Crabtree, Kay L.; Wood, Charles; Wojcicki, Janet M.; Minhas, Veenu; Kankasa, Chipepo; Mitchell, CharlesBackground: Human herpesvirus 8 (HHV-8) infection occurs in early childhood and is associated with human immunodeficiency virus type 1 (HIV-1) infection and risk for Kaposi sarcoma, but behaviors associated with HHV-8 transmission are not well described. Methods: We enrolled and followed a prospective cohort of 270 children and their household members to investigate risk factors for HHV-8 transmission in Lusaka, Zambia. Results: We report an incidence of 30.07 seroconversions per 100 child-years. Independent risk factors for HHV-8 incident infection included having a child who shared utensils with a primary caregiver (hazards ratio [HR], 2.33; 95% confidence interval [CI], 1.49-7.14), having an increasing number of HHV-8-infected household members (HR, 1.27; 95% CI, 1.09-2.79), and having >/=5 siblings/children in the household (HR, 2.24; 95% CI, 1.03-4.88). Playing with >5 children a day was protective against infection (HR, 0.54; 95% CI, .33-0.89), as was increasing child age (HR, 0.96; 95% CI, .93-.99). Conclusions: This is the first study to find a temporal association between limited child feeding behaviors and risk for HHV-8 infection. Child food- and drink-sharing behaviors should be included in efforts to minimize HHV-8 transmission, and households with a large number of siblings should receive additional counseling as childhood infections occur in the home context. ItemRapid appraisal project: Marik protocol for sepsis management(2018-11) Klein*, Emily; Aguilar, Brianna; Holm, Ashley; Robinson, Britta; Hoppe, Lesa, PhD, MSN, RNDo patients diagnosed with severe sepsis who are treated with hydrocortisone, thiamine, and vitamin C have a better prognosis than those treated with the current standard practice? Through extensive searching of the Cochrane Collection, PubMed, and the Bryan College of Health Sciences Library, this medication regimen effectiveness was analyzed. To research this regimen, three primary research articles were chosen. Because this topic is new, available research was limited. Criteria for the primary article included the full medication regimen, a critical care setting, and the diagnosis and prognosis of sepsis. Additionally, one systematic review was chosen that analyzed the effectiveness of hydrocortisone in the treatment of sepsis. To supplement the article and review, a registered nurse was interviewed. With over 30 years of experience in the intensive cardiac unit at an urban hospital, she detailed her experiences with sepsis and shared that this protocol has been in discussion at intensive care conventions. Through the research, we found that this protocol decreased mortality by 32%, decreased the need for dialysis by 17%, and decreased vasopressor use by an average of 35 hours. Ultimately, this medication regimen shows great potential but will need to be studied further before it becomes standard practice. ItemFormal mentor toolkit(Bryan College of Health Sciences, 2018-12) Baer, Nichole; Barker, Molle; Melcher, Candace R.BACKGROUND: The nursing profession is plagued with a major nursing shortage due to the aging population of the nursing workforce, baby boomers and due to the increasing demands of the healthcare organizations. The turnover rate of new graduate nurses within the first year of employment only compounds this problem. Up to 50% of new graduate nurses change jobs during their initial year of employment, 13% contemplate leaving their job, and some leave the professional altogether (Boamah & Laschinger, 2015). Nurse residency programs (NRP) were found to decrease the 12 month turnover rate from 36% to 6.5% (Trepanier, Early, Ulrilich, & Cherry, 2012). In addition, the retention rate of new graduate nurses assigned to a mentor was 91% compared to non-mentored nurses with a retention rate of 66% (Schroyer, Zellers, & Abraham, 2016). PURPOSE: The purpose of this project was to focus on developing a toolkit to be utilized as a resource for implementing a formal mentor program to support the retention of new graduate nurses. The population of interest were new graduate nurses participating in the Nurse Residency Program at a Midwestern regional hospital. METHOD: Researchers reviewed literature that supports a formal mentor program. Based off of information obtained in the literature, the formal mentor program was developed. This proposal was then formally presented to key stakeholders, including the Chief Nursing Officer. RESULTS: After presenting the toolkit to the key stakeholders, dialogue took place that afforded the opportunity for further clarification and suggestions to take place. Recommendations from the stakeholders for various changes were made and notes were taken of their questions and recommendations. Key recommendations for strengthening the formal mentor program were: offer the mentor program to experienced nurses new to the organization as well as to the new graduate nurses; change the timing of the initiation of the program from 6 months to 12 months for the new graduate nurses; offer the formal mentor program to experienced nurses beginning just prior to their orientation ending; the mentor may need to be assigned to more than one mentee due to the volume of new hires or experienced nurses interested in participating in the program; the mentor/mentee would ideally be paired together from the same unit however if the volume of new hires outnumbered the qualified mentors, mentors from sister units could be assigned to the mentee. CONCLUSION: The results of the presentation of the formal mentor program to the key stakeholders was favorable. Additional collaboration to further develop the formal mentor program is necessary for further development and successful implementation. ItemNutrition Related to Wound Healing(2018-12) Grieve, Mackenzie; Wurtz, Laura; Hoppe, Lesa. PhD, MSN, RNThrough clinical experiences amongst patients with wounds, an inquiry arose regarding interventions that could be used to expedite the healing process—specifically nutrition. Through extensive searching of Bryan Fusion, inclusive of scholarly works found in databases such as PubMed and CINAHL, articles were found comparing wound healing and nutrition. An interview with an expert clinician was also conducted. A primary outcome of this literature review process was the finding that malnutrition is highly prevalent in patients with pressure ulcers. According to our research, proper nutrition and supplementations are proven to be beneficial in wound prevention and healing. The nutrients that had the greatest effect on wound healing include arginine, zinc, antioxidants, and protein supplementation. ItemAssessing undergraduate nursing students' confidence utilizing simulated bedside shift report(Bryan College of Health Sciences, 2018-12) Bratt, Julie; Ehmke, Courtney; Park, Emily; Barbara Sittner, Ph.D., RN, APRN-CNS, ANEF. Bryan College of Health SciencesPURPOSE: The purpose of this quality improvement project is to use simulation training for bedside nurse reporting with undergraduate nursing students to increase their confidence levels. BACKGROUND: Typically, nursing students are not taught how to perform handoff communication systematically; handoff reporting is learned through vicarious observations and apprenticeship experiences. As a result, they may observe many clinical handoff reports but lack the ability to independently conduct effective reports during care transitions and critique the reports of others (Lee et al, 2016). Clinical simulation training helps to ensure participants receive the same content, affording them the opportunity to practice new skills, and help to work through challenging situations and learn from their own and others' mistakes in a safe environment (Connolly, 2017). METHOD: An educational power point was reviewed by the students at the beginning of their simulation day. Students completed a 4 question pre and post survey developed by the research team to assess student confidence utilizing SBAR format. RESULTS: Results were analyzed using a Paired T test. The average pre and post scores have a p value of <0.0001, and it was found that 267 percent of undergraduate nursing students said they strongly agreed feeling confident when delivering bedside shift report after participating in a simulated environment. CONCLUSIONS: The results of this survey indicate the need for continued bedside shift report during simulation experiences to increase future nursing students' confidence. ItemCompassion awareness(Bryan College of Health Sciences, 2018-12) Belz, Marsha; Gerken, Ashton; Kimminau, Linda; Barbara Sittner, Ph.D., RN, APRN-CNS, ANEF. Bryan College of Health Sciences.PURPOSE: To increase awareness and educate on compassion fatigue versus compassion satisfaction, with two progressive care units, at a midwestern medical center. Following education, does this improve the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) nursing composite scores? BACKGROUND: Since the implementation of the HCAHPS, hospital reimbursement has been associated with quality metrics and patient experience ratings. The transparency and focus on metrics has created additional stress on critical care nurses. These nurses report less capacity for compassionate feelings toward patients when they perceive their role expectations are not met. METHOD: There were 29 participants involved. The nurses were educated on compassion satisfaction and compassion fatigue and were invited to take the Professional Quality of Life survey (ProQOL). Chi-Square analyzes were used to find the relationships between burnout and age, education, unit tenure and nursing experience. A statistically significant relationship was found between burnout and unit tenure (chi sq = 15.3, p <.009). Nurses, with a tenure between one and three years were almost three times as likely to experience burnout compared to nurses with less than one year and more than three years of unit tenure. A statistically significant relationship was also found between burnout and nursing experience (chi sq = 10.6, p <.05). However, there was no correlation with the HCAHPS. CONCLUSIONS: Strategies were provided to the nurse managers on ways to identify and prevent compassion fatigue. These recommendations include: utilizing the ProQOL, being a transformational leader and implementing a meaningful recognition program. ItemProvost Colloquium: Master of Science in Nursing. Program brochure(Bryan College of Health Sciences., 2018-12-05)This is the program brochure for the capstone projects for the December, 2018 Bryan College of Health Sciences Master of Science in Nursing graduates. The brochure includes the Bryan College of Health Sciences MSN Program Philosophy and MSN Program Outcomes. The three capstone project abstracts presented are: Julie Bratt, Courtney Ehmke & Emily Park, "Assessing undergraduate nursing confidence utilizing simulated bedside shift report"; Marsha Belz, Ashton Gerken & Linda Kimminau, "Compassion awareness"; and Nicole Baer, Molle Barker & Candace Melcher, "Formal mentoring program." ItemWhat current research can teach medical personnel about sepsis management and treatment(Nebraska Academy of Sciences, 2019-04-12) Klein*, Emily; Holm, Ashley; Aguilar, Brianna; Robinson, BrittanyDo patients diagnosed with severe sepsis who are treated with hydrocortisone, thiamine, and vitamin C have a better prognosis than those treated with the current standard practice? Through extensive searching of the Cochrane Collection, PubMed, and the Bryan College of Health Sciences Library, this medication regimen effectiveness was analyzed. To research this regimen, three primary research articles were chosen. Because this topic is new, available research was limited. Criteria for the primary article included the full medication regimen, a critical care setting, and the diagnosis and prognosis of sepsis. Additionally, one systematic review was chosen that analyzed the effectiveness of hydrocortisone in the treatment of sepsis. To supplement the article and systematic review, a critical care nurse was interviewed. With over 30 years of experience in the intensive cardiac unit at an urban hospital, she detailed her experiences with sepsis and shared that this protocol has been in discussion at intensive care conventions. Through research, we found that this protocol decreased mortality by 32%, decreased the need for dialysis by 17%, and decreased vasopressor use by an average of 35 hours. Ultimately, the current research on this medication regimen shows great potential in benefiting patient outcomes. ItemRapid Appraisal Project: Nutrition Related to Wound Healing(2019-04-22) Grieve, Mackenzie; Wurtz, LauraThrough clinical experiences amongst patients with wounds, an inquiry arose regarding interventions that could be used to expedite the healing process—specifically nutrition. Through extensive searching of Bryan Fusion, inclusive of scholarly works found in databases such as PubMed and CINAHL, articles were found comparing wound healing and nutrition. An interview with an expert clinician was also conducted. A primary outcome of this literature review process was the finding that malnutrition is highly prevalent in patients with pressure ulcers. According to our research, proper nutrition and supplementations are proven to be beneficial in wound prevention and healing. The nutrients that had the greatest effect on wound healing include arginine, zinc, antioxidants, and protein supplementation. ItemStandardizing the Evaluation of Service Learning(2019-05) Hunt, Tiffany AnnAbstract Background: Service learning is an educational pedagogy that provides students with an opportunity to apply classroom knowledge to real-life situations. There are three components of service learning: course outcomes, service, and reflection. One barrier to incorporating service learning into nursing curriculum is the lack of a standardized measurement to evaluate students’ service learning experiences. Purpose: The purpose of this study was two-fold: first, to develop a standardized rubric to evaluate nursing students’ experiences of service learning within an undergraduate nursing school program, and second, to test the reliability and validity of the newly developed measurement tool, the Hunt Service Learning Evaluation (HuSLE) rubric to evaluate students’ experiences of service learning. Methods: This descriptive study used a convenience sample of five undergraduate faculty who provided data for the development of the HuSLE rubric’s psychometric properties. Results: Analyses indicated that overall, the items within the HuSLE rubric have a high percentage of agreement among raters; six out of the eight items were statistically significant. The reflection domain had the greatest amount of variation between raters. The content validity index (CVI) completed by the raters was statistically significant during phase I. The CVI completed by the content experts was statistically significant for all items except number of service hours, type of service, and reflection-bridging the experience. Conclusion: This study demonstrated the design and development of a standardized rubric used to evaluate undergraduate nursing students’ experiences of service learning that has not yet been reported in the literature. A standardized rubric with statistically significant validity was established. The HuSLE rubric is reliable and valid and may be an easy tool for nurse educators to use as a strategy for measuring nursing students’ service learning experiences. ItemDelayed Umbilical Cord Clamping(2019-05) Boller, Southern; Young, Shayna; Hoppe, Lesa. PhD, MSN, RNThe purpose of this research project was to look at the effect and assess the delaying of the umbilical cord clamping at birth. The articles obtained were from CINAHL and PubMed. The PICO question that gave results included: in neonates (greater than 34 weeks gestation), does delayed umbilical cord clamping, compared to early umbilical cord clamping, affect hematocrit/hemoglobin. This evidence-based practice of delayed cord clamping has been implemented in medical centers around the country and world as the beneficial effects has been shared through research and trials. Delayed umbilical cord clamping, as compared to early, has shown benefits including a decrease in mortality, an increase in the hemoglobin and hematocrit, and an overall increase in the baby's well-being, especially in pre-term infants. This research included data sources from randomized controlled trials and systematic reviews - meta analysis. The studies can be applied to a general population through the labor and delivery process. One specific finding of the research articles was the commonalities in relationship to hematological components related to delayed cord clamping. The intervention group saw a higher hematocrit and hemoglobin without increases in hyperbilirubinemia or symptomatic polycythemia. This leads to an increase in oxygen available to the newborn, which helps to increase the oxygen saturation and better perfuse the organs. The infant's vital signs will show an improvement including the cardiac output, heart rate, and blood pressure. Other findings included in the research were a decrease in mortality in infants and a higher APGAR score at birth. The delaying of the clamping caused a reduction of the incidence of blood transfusions, infection, and sepsis. Many of the benefits were documented later on in the infants' life. This included a lower incidence of anemia and iron deficiency. The selected studies gave collected data and reviewed bias related to delayed versus early umbilical cord clamping. The researchers saw many benefits through the subjects including improvement to the infant's health and development throughout their lifespan. The benefits included an increase in hemoglobin and hematocrit, a higher APGAR score, lower bilirubinemia, and lower incidence of hospital mortality. Delayed umbilical cord clamping has shown to be safe, beneficial, and is now being implemented in health care facilities around the world. ItemFactors Influencing the Recruitment and Hiring of Early Career Nurse Faculty(2019-05) Sladky, Katie AnnThe nursing faculty and subsequent nursing shortages have plagued the profession for decades with little progress made in altering the trajectory of the problem (AACN, 2005; IOM, 2010; NLN, 2017). Primary influences on the faculty shortage include later entry into faculty roles, the aging of faculty, and early retirements, and a logical solution is to recruit nurses to faculty roles earlier in their careers. The purpose of this study was to examine factors relating to recruitment strategies and hiring practices used by administrators of undergraduate, prelicensure nursing programs for early career nursing faculty. This study contributes new knowledge about administrators’ perspectives on hiring well-qualified young nurses for faculty roles and the most effective recruitment strategies for that demographic. A cross-sectional, descriptive survey design was used. The sample consisted of 80 nursing program administrators from eight Midwestern states. The survey tool was developed by the researcher based on the literature and consisted of 15 questions regarding hiring practices for open faculty positions and recruitment methods that were evaluated for how effective they could be, their frequency of use, and how effective they have been if used. Results of the study showed that nursing program administrators have a strong desire to hire well-qualified young nurses for faculty roles but that this population is not applying for open faculty positions as frequently as older nurses. The strategies that have been most effective for early career nurse faculty recruitment are recruiting individuals recommended by current faculty, the direct recruitment of individuals, and engaging in direct conversations encouraging a future faculty role. These results demonstrate the need for intentionality in recruiting potential candidates for academic careers and the importance of shedding a positive light on nursing education and the faculty role. Administrators, faculty, and all other stakeholders within nursing education must take ownership in putting these methods into action. ItemNitrous oxide use in labor(2019-05) Nevels, Kelci; Petsch, Priscilla; Sevcik, Emily; Hoppe, Lesa, PhD, MSN, RNThere is a great amount of literature exploring the effects of nitrous oxide (N2O) as a method of pain relief for laboring women. However, a majority of this research was published prior to 2010 and conducted in other countries. Since the emergence of epidural analgesia, N2O has not been the method of choice for labor pain management in the United States. Despite this trend, many hospitals have recently seen a reemergence of this less expensive and less invasive gas. Many women are choosing this method of pain relief due its benefits of having a shorter half-life, ability to encourage feelings of empowerment, and the requirement of fewer interventions that would be needed with epidural analgesia (e.g., bladder catheterization, intravenous fluid bolus, blood pressure monitoring). This gas is also an appropriate option for women if epidural analgesia is contraindicated, ineffective, or inadequate. Since this drug is self-administered by the patient, there are minimal risks of adverse effects for hospital staff and caregivers. Side effects of N2O inhalation include dizziness, nausea, vomiting, and drowsiness. Research on this intervention has not found a significant relationship between maternal N2O inhalation and neonatal APGAR scores. Overall, many studies are indicating positive benefits of N2O inhalation as a method of pain management during labor. Unfortunately, a majority of these studies were of poor quality with bias and inconsistency among expected outcomes. Furthermore, many of these studies are qualitative, gaining mothers' views of N2O use after deliveries. Clearly, further quantitative research regarding this form of pain management during labor is needed to accurately assess its effectiveness as well as the potential risks to mother, neonate, and medical staff. ItemAn Assessment of Burnout and Associated Characteristics among Midcareer Prelicensure BSN Faculty(2019-05) Bentjen, MelindaThe United States is projected to experience a shortage of registered nurses due to aging baby boomers and growing need for health care. Nursing faculty shortage directly impacts the supply and demand for nurses. Each career stage of nursing faculty, early, middle, and late, have components that effect the work group. There is a need to explore midcareer nursing faculty based on the majority of faculty fall in this career stage and have many challenges in work-life. The purpose of this study is to understand more about the pragmatic issues of education by investigating the prevalence of active, Midwestern, prelicensure, midcareer Bachelor of Science in Nursing (BSN) faculty experience of burnout. The main aim is to discover if midcareer prelicensure BSN faculty experience burnout. The Maslach Burnout Inventory-Educators Survey (MBI-ES) was used to collect data from a sample of 44 Midwestern midcareer nursing faculty. In this descriptive, cross-sectional design, midcareer nursing faculty were chosen by a convenience sampling. The results of frequency distribution and t tests (p=0.0086) showed that midcareer nursing faculty (mean=23.55) had a significantly higher level of burnout based on their Emotional Exhaustion Subscale score compared to postsecondary teachers (mean=18.57). Pearson’s correlation coefficients found that midcareer nursing faculty who exercised (2-tailed=0.007) and taught more credit hours (2-tailed=0.14) in a semester had a low level of burnout based on their Personal Accomplishment Score. Results of this study indicate that midcareer nursing faculty have high Emotional Exhaustion. Findings from this study suggest that midcareer nursing faculty who have a hobby, exercise, and teach more credit hours in a semester demonstrate a high Personal Accomplishment. Further investigation into the work/life balance of midcareer nursing faculty would assist in supporting professional development and mentoring program. ItemThe Lived Experience of College Faculty Following Student Suicide: A Phenomenological Inquiry(2019-05) Summers, MichelleAbstract The purpose of this qualitative phenomenological study was to explore the lived experience of college faculty following student suicide. Doka’s Theory of Disenfranchised Grief was used as a theoretical framework. The research methodology of phenomenology was utilized for this study. Six participants completed face-to-face interviews and shared their complete and personal experience with student suicide. Data were analyzed using Tesch’s eight steps. The participants’ stories yielded themes of missed clues, postvention, awareness of student problem, guns, and loss of potential. Faculty members who have experienced the suicide of a student are often faced with many challenges. Overall, the participants expressed a belief that they failed to notice clues of students’ suicidal ideations, and the belief that they lacked formal training in the area of mental health. The participants also expressed a need for postvention, including debriefing, following a student suicide. A lack of available resources for students with mental health needs was highlighted, along with the challenges associated with being unable to force a student to engage in therapy. Based upon the findings of this study, there is a need to acknowledge the feelings and emotions of faculty members following student suicide. Grief is a unique and personal experience. The results of this study suggest that faculty members need training and support in suicide prevention, intervention and postvention. ItemWhat Current Research Can Teach Medical Personnel About Sepsis Management and Treatment(2019-10-19) Klein*, Emily; Aguilar, BriannaDo patients diagnosed with severe sepsis who are treated with hydrocortisone, thiamine, and vitamin C have a better prognosis than those treated with the current standard practice? Through extensive searching of the Cochrane Collection, PubMed, and the Bryan College of Health Sciences Library, this medication regimen effectiveness was analyzed. To research this regimen, three primary research articles were chosen. Because this topic is new, available research was limited. Criteria for the primary article included the full medication regimen, a critical care setting, and the diagnosis and prognosis of sepsis. Additionally, one systematic review was chosen that analyzed the effectiveness of hydrocortisone in the treatment of sepsis. To supplement the article and systematic review, a critical care nurse was interviewed. With over 30 years of experience in the intensive cardiac unit at an urban hospital, she detailed her experiences with sepsis and shared that this protocol has been in discussion at intensive care conventions. Through research, we found that this protocol decreased mortality by 32%, decreased the need for dialysis by 17%, and decreased vasopressor use by an average of 35 hours. Ultimately, the current research on this medication regimen shows great potential in benefiting patient outcomes.