Faculty, administrators and staff of the Bryan College of Health Sciences are encouraged to submit their professional scholarship to the Scholarly Works Archives. This might include, but is not limited to, peer-reviewed journal articles; theses or dissertations; abstracts of books or book chapters; conference papers or presentations; technical reports; white papers; abstracts or presentations from College symposia; professional website content. Selected student works will be included upon the recommendation of a faculty member.
The Archives can host works in a wide variety of formats, including links to publisher pages, PDF versions of open access manuscripts, PowerPoint presentations, images and audio-visual materials.
Authors interested in having their scholarly works included in the Archives should contact the Director of Library Services by emailing email@example.com.
Non-exclusive license agreement:
Authors will be required to sign a Non-Exclusive Distribution license for each item submitted to the institutional repository. Full-text of the work will be uploaded into the repository if the author owns the copyright to the work, or has written permission from the publisher to add the work to an archive. If archiving permission is not granted, links will be made to the publisher content for the article.
(The Journal of Experimental Microbiology & Immunology+, 2017) Christensen, Collin J.; Anderson, Kelsi L
Essential oils have risen in popularity as “all natural” alternatives used to treat a myriad of conditions. To begin to elucidate the antibacterial properties of essential oils, we tested the effectiveness of lemongrass oil (LGO), tea tree oil (TTO), and willow bark extract (WBE) against Staphylococcus aureus growth. To do so, a Methicillin-Resistant strain of Staphylococcus aureus (USA300) was exposed to each oil using disk diffusion assays. Of the oils, LGO had the greatest zone of inhibition. The Minimum Inhibitory Concentration (MIC) of both LGO and citral (the primary chemical component of LGO) was determined in macro-broth cultures; exposure to increased concentrations of each resulted in dramatic cell death as determined by cell growth assays. To begin to determine the molecular mechanisms underlying the observed antibacterial effects, we exposed cells to a sub-inhibitory concentration of citral and hybridized the RNA to Affymetrix GeneChips®. Transcripts differentially affected in citral- versus mocktreated cells represent virulence factors, hypothetical proteins, and intergenic regions. Taken together, these results demonstrate that LGO exhibits antibacterial properties against a highly pathogenic bacterial species that is
exceedingly resistant to the currently available antibiotics.